The thesis presents a study, conservation strategies, and an adaptive design for Palazzo Minotto in Venice. Following the methodology of Egle Renata Trincanato, it investigates the building's historical metamorphoses through preserved traces within the present architecture of the palace, while analyzing its present spatial patterns, conditions, and potentials. Supported by historical cartography, archival research, and on-site analysis, the study reconstructs the palace's complex evolution and its urban context from the fourteenth century onward. The conservative and design proposals are strongly based on the results of the research findings and aim to reactivate the mentally and physically abandoned Palazzo Minotto in response to current needs of the city and its residents. In this context, Venice needs a future, and its severe population decline, over-tourism, intense housing pressures, and many vacant houses make it essential to preserve its academic community through truly affordable housing and adaptable spaces for residents, given that the city has already enough museums and tourist infrastructure.